We don’t know, we aren’t given any specific timing in the Bible, when the Seals are being opened, but if you look at the world today and everything going on - we can find a place where it fits.
The first and second Seals: conquering and conflict on earth could be happening now. Especially when we see the current conflicts with Ukraine and Israel. There is movement on the world stage with China, Asia overall, and Europe, to re-shape and gain control of sovereign nations. It’s only going to get worse.
The pandemic of 2019 is a good example - and we see the World Health Organization stepping in with a new treaty (not yet accepted, but still in the works) that would give them global control on pandemic declarations and how each country responds - basically giving up control of sovereign health care to a world organization. More information can be found at this link:
But we can say we haven’t seen the sixth Seal yet, where the sun and moon change in appearance. There is much much more, but we know that this is expected to come - let us look at Revelation 13 to learn more about the world affairs.